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in-situ characterization 1

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3D Bioprinting: A Novel Avenue for Manufacturing Tissues and Organs Review

Bin Zhang, Lei Gao, Liang Ma, Yichen Luo, Huayong Yang, Zhanfeng Cui

Engineering 2019, Volume 5, Issue 4, Pages 777-794 doi: 10.1016/j.eng.2019.03.009

Abstract: describe the recent advancements of 3D bioprinting in fabricating cell-laden artificial tissues and organsThe development of organs-on-chips utilizing 3D bioprinting technology for drug discovery and toxicity

Keywords： Three-dimensional bioprinting Solid tissues Hollow tissues Organs-on-chips Tissue engineering Drug

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Study on the Theory of Five Organs Correlation from Five Elements to Five Organs Correlation

Deng Tietao,Zheng Hong

Strategic Study of CAE 2008, Volume 10, Issue 2, Pages 7-13

Abstract: To rectify this, Chine se medicine correlates five organs with five elements, which not only maintainsThus, Chinese medicine theor ies can be wound up to “the theory of five organs correlation&rdquo

Keywords： Chinese medicine theory of five organs five elements

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Arsenic and chromate removal from water by iron chips-Effects of anions

ZHANG Ruihua, SUN Hongwen, YIN Jin

Frontiers of Environmental Science & Engineering 2008, Volume 2, Issue 2, Pages 203-208 doi: 10.1007/s11783-008-0036-6

Abstract: study is to estimate the removal efficiency of As and Cr (VI) by one kind of industrial waste – iron chips

Keywords： phosphate removal efficiency industrial typical inorganic

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Nanosheet Chips Poised to Rescue Moore’s Law

Robert Pollie

Engineering 2021, Volume 7, Issue 12, Pages 1655-1656 doi: 10.1016/j.eng.2021.11.008

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Light-Based Chips Promise to Slash Energy Use and Increase Speed

Mitch Leslie

Engineering 2021, Volume 7, Issue 9, Pages 1195-1196 doi: 10.1016/j.eng.2021.07.005

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What will the future hold for artificial organs in the service of assisted reproduction: prospects and

Mara Simopoulou, Konstantinos Sfakianoudis, Petroula Tsioulou, Anna Rapani, Polina Giannelou, Nikolaos Kiriakopoulos, Agni Pantou, Nikolaos Vlahos, George Anifandis, Stamatis Bolaris, Konstantinos Pantos, Michael Koutsilieris

Frontiers of Medicine 2019, Volume 13, Issue 6, Pages 627-638 doi: 10.1007/s11684-019-0697-5

Abstract: Cutting edge research on animal models introduced this concept, along with the development of artificial organsTo date, the successful clinical application of artificial reproductive organs in humans is not feasibleThe application of these artificial organs could provide a solution to infertility cases with no other

Keywords： artificial ovary artificial uterus artificial gametes assisted reproduction considerations in vitro fertilization

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RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs

Xin Zou, Ke Chen, Jiawei Zou, Peiyi Han, Jie Hao, Zeguang Han

Frontiers of Medicine Pages 185-192 doi: 10.1007/s11684-020-0754-0

Abstract: exhibit non-respiratory symptoms, such as kidney failure, implying that 2019-nCoV could also invade other organsTo construct a risk map of different human organs, we analyzed the single-cell RNA sequencing (scRNA-seqThrough scRNA-seq data analyses, we identified the organs at risk, such as lung, heart, esophagus, kidneyBased on the findings, we constructed a risk map indicating the vulnerability of different organs to

Keywords： 2019-nCoV ACE2 single-cell RNA-seq

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Explanation of Pathological Changes of Five Zang Organs in Wuxingshengke

吉良展,陈光曼

Strategic Study of CAE 2006, Volume 8, Issue 4, Pages 94-94

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Individualized Pixel Synthesis and Characterization of Combinatorial Materials Chips Article

Xiao-Dong Xiang, Gang Wang, Xiaokun Zhang, Yong Xiang, Hong Wang

Engineering 2015, Volume 1, Issue 2, Pages 225-233 doi: 10.15302/J-ENG-2015041

Abstract:

Conventionally, an experimentally determined phase diagram requires studies of phase formation at a range of temperatures for each composition, which takes years of effort from multiple research groups. Combinatorial materials chip technology, featuring high-throughput synthesis and characterization, is able to determine the phase diagram of an entire composition spread of a binary or ternary system at a single temperature on one materials library, which, though significantly increasing efficiency, still requires many libraries processed at a series of temperatures in order to complete a phase diagram. In this paper, we propose a "one-chip method" to construct a complete phase diagram by individually synthesizing each pixel step by step with a progressive pulse of energy to heat at different temperatures while monitoring the phase evolution on the pixel in situ in real time. Repeating this process pixel by pixel throughout the whole chip allows the entire binary or ternary phase diagram to be mapped on one chip in a single experiment. The feasibility of this methodology is demonstrated in a study of a Ge-Sb-Te ternary alloy system, on which the amorphous-crystalline phase boundary is determined.

Keywords： combinatorial materials chip phase diagram pixel synthesis in-situ characterization phase-boundary determination

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Data mining of microarray for differentially expressed genes in liver metastasis from gastric cancer

Ling XU MM, Feng WANG MM, Xuan-Fu XU MD, Wen-Hui MO BM, Rong WAN MD, Chuan-Yong GUO MD, Xing-Peng WANG MD,

Frontiers of Medicine 2010, Volume 4, Issue 2, Pages 247-253 doi: 10.1007/s11684-010-0027-4

Abstract: Tumor metastasis is the leading cause of death for gastric cancer. Metastasis is the main reason for the failure of clinical treatment for gastric cancer. In order to find metastasis-related genes and abnormal signal transduction pathway of high-invasive gastric cancer, samples of gastric cancer with liver metastasis were collected for microarray detection; up-regulated or down-regulated genes in all three cases were simultaneously screened out. Subsequently, from the preliminary screened genes, molecular pathways possibly impacting liver metastasis from gastric cancer were investigated by the Gene Cluster with Literature Profiles (GenCLip) analysis software. Many biological effects including apoptosis have been validated. Functional analysis of differentially expressed genes revealed that a variety of biological pathways, such as blood circulation and gas exchange, vasodilation and vasoconstriction regulation, and immune defense, could be significantly activated. Besides, gene sequences, specific keywords or gene regulatory networks were further searched by GenCLiP. We conclude that data mining allows to quickly identify a series of special signal transduction pathways involving abnormally expressed genes.

Keywords： gastric carcinoma metastasis signal transduction gene chips